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thirteen,30 Additionally, CCL2 is documented to boost osteoclastogenesis by inducing the expression of receptor activator of NF-?B (RANK) by osteoclast progenitors.31 RANK ligand (RANKL) further encourages the differentiation of osteoclast progenitors into useful osteoclasts, which could aggravate DP by triggering alveolar bone resorption.32 These